Illustration showing a chimeric antigen receptor (CAR) T cell (blue) being used to a treat non-Hodgkins lymphoma (purple). Surrounding cells include healthy white blood cells (pink) and red blood cells (red discs). Diffuse large B-cell lymphoma (DLBCL) is a common type of non-Hodgkin lymphoma, or cancer of the lymphatic system. It affects B lymphocytes, a white blood cell that produces antibodies to fight against infection. DLBCL normally develops in the lymph nodes causing uncontrollable growth of the B lymphocytes. It is typically fast-growing, and requires combined chemotherapy and immunotherapy. CAR-T therapy is a type of immunotherapy that genetically modifies a patients own T cells, another form of white blood cell, to recognise and destroy cancer cells.