Illustration of rhinofacial conidiobolomycosis in a man with a close-up view of the microscopic fungus Conidiobolus coronatus, the causative agent of the disease. This chronic mycosis affects the nose and face. The infection occurs when the fungus enters the body through a cut or wound on the skin or through the nose. The fungus then grows in the tissues, causing inflammation and swelling, which can lead to deformities in the nose and face. The infection is usually slow-growing and painless, but it can cause discomfort and affect the patient's quality of life. Symptoms of rhinofacial conidiobolomycosis include facial swelling, redness, and thickening of the skin, nasal obstruction, and discharge. The infection can also cause vision problems if it spreads to the eyes. It is a rare condition, but it can occur in immunocompromised individuals, those with underlying medical conditions, or those who live in areas with high fungal exposure.