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Cas9 from Streptococcus pyogenes complexed with RNA and DNA. Molecular model of Cas9 (not shown) from Streptococcus pyogenes complexed with RNA and DNA. GeoCas9 and the Gag-pol polyprotein have been removed in order to have an unobstructed view of the nucleic acids. The RNA is shown in green, a DNA (length 51) in blue, a DNA (length 17) in yellow-orange and a DNA/RNA in pink.

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