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Cas12g complexed with sgRNA. Molecular model of Cas12g (showed in purple) mediating single guide RNA cleavage (sgRNA shown in cyan). Cas12g is an endonuclease belonging to the type V RNA-guided CRISPR-Cas family. It is known for its ability to cleave RNA substrates using a conserved endonuclease active site located in the RuvC domain.

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