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Heart disease, illustration. Fibrosis and calcified endocarditis of the heart valves resulting in impaired function that lead to enlargement of the heart chambers with hypertrophy of its tissues. This condition is accompanied by chronic exhaustion of cardiac function and premature death. From Bollinger, O. 1901 Atlas und Gundriss der Pathologischen Anatomie, vol 1. Lehmann, Munich.
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