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Illustration of a cholesterol molecule (spheres) binding to the G-protein coupled receptor (GPCR) Ste2 from the yeast Saccharomyces cerevisiae. Sre2 is a yeast mating receptor that binds pheromone molecules. Binding of a pheromone induces a signalling cascade that prepares the cell for sexual reproduction. The receptor is being studied as possible drug target for fungal infections.

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