Notum (palmitoleoyl-protein carboxylesterase) complexed with inhibitor ARUK3004470 , molecular model. The image shows a ribbon rendering of notum with the inhibitor shown as spacefilling element-coloured molecule. Notum is a carboxylesterase that acts as a key negative regulator of the Wnt signalling pathway by specifically mediating depalmitoleoylation of WNT proteins.
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Creative#:
TOP28926488
Source:
達志影像
Authorization Type:
RM
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須由TPG 完整授權
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