Prenyl-binding protein PDE6D and inhibitor, illustration
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Creative#:
TOP28926129
Source:
達志影像
Authorization Type:
RM
Release Information:
須由TPG 完整授權
Model Release:
n/a
Property Release:
n/a
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No
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Illustrationofthesmallmoleculeinhibitor(s)-5(black)boundtoprenyl-bindingproteinPDE6D(phosphodiesterase6deltapink).InhibitionofPDE6DpreventsitbindingtoandactivatingtheKRASoncogeneproduct.ActivationofKRASpromotescellgrowthandproliferation.MutationsinKRASleadtocancertheuncontrolledgrowthandproliferationofcells.ThereforeinhibitorsofPDE6Darebeinginvestigatedasanticancerdrugs.
(black)(phosphodiesterase(s)-56ActivationIllustrationInhibitionKRASKRASKRASMutationsPDE6DPDE6DPDE6DThereforeactivatingandandandanticancerareasbeingbindingboundcancercellcells.deltadrugs.growthgrowthininhibitorinhibitorsinvestigateditleadmoleculeofofofofofoncogenepink).prenyl-bindingpreventsproduct.proliferationproliferation.promotesproteinsmallthethethetototouncontrolled