Human telomeric DNA G-quadruplex, illustration
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Creative#:
TOP28926121
Source:
達志影像
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RM
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須由TPG 完整授權
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IllustrationofahumantelomericDNA(deoxyribonucleicacid)G-quadruplexboundtoanaphthalenediimide.TelomereDNAG-quadruplexesarefour-strandedDNAstructuresthatarefoundinthetelomereregionsattheendsofchromosomes.Telomeresareregionsofrepeatednon-codingnucleotidesthatpreventcodingnucleotidesbeinglostduringDNAreplication.Telomeresshortenovertimeandthisprocessisthoughttoplayaroleincancerandageing.Bindingofnaphthalenediimidescanstabilisethetelomeresandsotheyarebeinginvestigatedfortheiranticanceractivity.
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