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TOP27989879
Source:
達志影像
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RM
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differentiationanatomicalanatomybiologicalbiologybraincellscolouredconnectionconnectionsconnexionconnexionsdendritedendritesengineeredfalse-colourfalse-colouredgeneinducedpluripotentstemcellsipscsjunctionnervecellneuralneuriteneuritesneurogenin2neurologicalneurologyneuronneuroneneuronesneuronsoverexpressionphysiologicalphysiologypluripotentprocessprocessesscanningelectronmicrographscanningelectronmicroscopesemsynapsesynapses C056/2355 STEVEGSCHMEISSNER/SCIENCEPHOTOLIBRARY AnimalsHealthcare Neurone.Colouredscanningelectronmicrograph(SEM).Humanneuronsengineeredfrominducedpluripotentstemcells(iPSCs)throughNeurogenin2(Ngn2)overexpressionarewidelyusedtostudyneuronaldifferentiationmechanismsandtomodelneurologicaldiseases.TheseNgn2-inducedneurons(Ngn2-iNs)functionallymatureintomorphologicallycomplexandelectrophysiologicalactiveneurons.SpecimencourtesyofProfessorGiampietroSchiavoQueenSquareInstituteofNeurologyUCL.Magnification:x2500whenprinted10centimetreswide
(Ngn2)(Ngn2-iNs)(SEM).(iPSCs)2210ColouredGSCHMEISSNER/SCIENCEGiampietroHealthcare Neurone.HumanInstituteLIBRARY AnimalsMagnification:NeurogeninNeurologyNgn2-inducedPHOTOProfessorQueenSchiavoSpecimenSquareTheseUCL.activeanatomicalanatomyandandarebiologicalbiologybraincellcellscellscellscentimetrescolouredcomplexconnectionconnectionsconnexionconnexionscourtesydendritedendritesdifferentiationdifferentiationdiseases.electronelectronelectronelectrophysiologicalengineeredengineeredfalse-colourfalse-colouredfromfunctionallygeneinducedinducedintoipscsjunctionmaturemechanismsmicrographmicrographmicroscopemodelmorphologicallynerveneuralneuriteneuritesneurogeninneurologicalneurologicalneurologyneuronneuronalneuroneneuronesneuronsneuronsneuronsneurons.ofofoverexpressionoverexpressionphysiologicalphysiologypluripotentpluripotentpluripotentprintedprocessprocessesscanningscanningscanningsemstemstemstudysynapsesynapses C056/2355 STEVEthroughtotousedwhenwidewidelyx2500