![](https://nthumb.tpgimages.com/mid2_com_img/1339/24352/TOP22812566.jpg)
Phosphodiesterase enzymes (PDE) catalyze the degradation of cGMP, a molecular regulator of ion channels, cellular apoptosis (programmed cell death) and smooth muscle tissue. In particular, drugs that inhibit PDE-5 have been successful in the treatment of erectile dysfunction. This figure shows a model vardenafil (Levitra) bonded to the active site of PDE-5, which includes a magnesium(2+) ion (pink) and a zinc(2+) ion (grey). For vardenafil the atoms are represented as spheres and are colour-coded: carbon (black), hydrogen (white), nitrogen (blue), oxygen (red) and sulphur (yellow).
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Details
Creative#:
TOP22812566
Source:
達志影像
Authorization Type:
RM
Release Information:
須由TPG 完整授權
Model Release:
N/A
Property Release:
N/A
Right to Privacy:
No
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