M101 is a spiral galaxy like our Milky Way, but about 70% bigger. It is located about 21 million light years from Earth. X-rays from Chandra reveal the hottest and most energetic areas due to exploded stars, superheated gas, and material falling toward black holes. Infrared data from Spitzer shows dusty lanes in the galaxy where stars are forming, while optical data traces the light from stars. The images of M101 represent a sample of composites created with X-ray data from NASA's Chandra X-ray Observatory, infrared data from the Spitzer Space Telescope, and optical data collected by an amateur astronomer. Collaborations between professional and amateur astronomers reveal the possibilities and are intended to raise interest and awareness among the community of the wealth of data publicly available in NASA's various mission archives. This effort is particularly appropriate for this month because April marks Global Astronomy Month, the world's largest global celebration of astronomy. Release date April 23, 2014.