Color enhanced transmission electron micrograph (TEM) revealed the presence of coxsackie B3 virus particles (many highlighted in red), which were found within a specimen of muscle tissue. Coxsackie B3 virus is a member of the Picornaviridae family of viruses, and the genus, Enterovirus, as is the well-known, nearly eliminated, Poliovirus. The enteroviruses possess a positive-sense, single-stranded RNA ((+) ssRNA) genome. This virus, as is its brethren the Poliovirus and echovirus, are transmitted via the fecal-oral route, usually due to poor bathroom hygiene. The enteroviruses, therefore, are known to reside in the carrier's gut. The coxsackie B viruses is a serotypic group of enteroviruses which can cause mild gastrointestinal maladies, to frank myocarditis and, pericarditis which involves the heart, and the sac in which the heart resides within the chest.