Entitled: "Lyp矇maniaque" A woman is sitting on a bed, she has her knees drawn up to her chest, her body is turned to the left, face to the front. Lypemania translates to bipolar disorder, also known as bipolar affective disorder (and originally called manic-depressive illness), is a mental disorder characterized by periods of elevated mood and periods of depression. The elevated mood is significant and is known as mania or hypomania depending on the severity or whether there is psychosis. During mania an individual feels or acts abnormally happy, energetic, or irritable. They often make poorly thought out decisions with little regard to the consequences. The need for sleep is usually reduced. During periods of depression there may be crying, poor eye contact with others, and a negative outlook on life. The risk of suicide among those with the disorder is high at greater than 6% over 20 years, while self harm occurs in 30-40%. Other mental health issues such as anxiety disorder and drug misuse are commonly associated. The cause is not clearly understood, but both genetic and environmental factors play a role. Lithograph appeared in "Des maladies mentales considerees sous les rapports medicale, hygienique et medico-legal" by ?tienne Esquirol.