Flavia Domitilla Major (1st century CE); also known as Domitilla the Elder; was the first wife of Vespasian. She was the daughter of Flavius Liberalis; a humble quaestor's clerk; and was a formal mistress to an African knight before her marriage to Vespasian. She married Vespasian some time around 38 CE; and was the mother of future emperors Titus and Domitian; as well as Domitilla the Younger; and grandmother of Saint Flavia Domitilla. She died before Vespasian became emperor; some time around 65 CE.