Molecular model of caspase-1 complexed with an inhibitor. Caspase-1 is a protease, an enzyme that cleaves proteins. It is found predominantly in the cell cytoplasm, where it activates interleukin-1-beta, a molecule that mediates immune and inflammatory responses. Due to this activity caspase-1 is also known as ICE (interleukin-1-beta converting enzyme). Like other caspases it also plays a role in apoptosis (programmed cell death), but only when over-expressed.
px | px | dpi | = | cm | x | cm | = | MB |
Details
Creative#:
TOP16631183
Source:
達志影像
Authorization Type:
RM
Release Information:
須由TPG 完整授權
Model Release:
N/A
Property Release:
N/A
Right to Privacy:
No
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apoptosisartworkbiochemistrybiologicalbiologyblackbackgroundcaspase1complexcysteineproteasecysteine-asparticacidenzymeenzymesexecutionerproteinheterodimerheterodimericiceillustrationimmuneresponseinflammatoryresponseinhibitorinterleukin-1-betaconvertingmolecularmoleculemoleculesno-onenobodyoneprogrammedcelldeathproteaseproteinsingle
1acidapoptosisartworkbackgroundbiochemistrybiologicalbiologyblackcaspasecellcomplexconvertingcysteinecysteine-asparticdeathenzymeenzymesexecutionerheterodimerheterodimericiceillustrationimmuneinflammatoryinhibitorinterleukin-1-betamolecularmoleculemoleculesno-onenobodyoneprogrammedproteaseproteaseproteinproteinresponseresponsesingle