Linezolid molecule. Computer illustration showing the molecular structure of linezolid. Linezolid is an antibiotic with activity against methicillin-resistant Staphylococcus aureus (MRSA). It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. Atoms are represented as spheres: carbon (light blue), fluorine (light green), hydrogen (white), nitrogen (dark blue), oxygen (red).