Brain changes with ageing. Composite magnetic resonance imaging (MRI) scans showing changes due to ageing. Across top are three MRI scans of the normal brain of a 22-year-old man. Across bottom are three MRI scans of the normal brain of a 96-year-old woman. The elderly woman's brain shows some 'involutional changes' but these are probably normal for her age. Brain shrinkage is shown by extensive white areas, particularly visible in the axial and sagittal sections (lower left and lower centre). The scans at right are coronal sections.