![](https://nthumb.tpgimages.com/mid2_com_img/1339/8480/TOP10705353.jpg)
Anaesthetic inhibiting an ion channel. Computer model showing the structure of propofol anaesthetic drug molecules (spheres, lower left and right) bound to a pentameric ligand-gated ion channel (pLGIC, grey and blue). Propofol is used for inducing and maintaining general anaesthesia. pLGICs are targeted by general anaesthetics such as propofol which bind to the extracellular interface between the channel's five monomers (subunits) and inhibit its action.
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Details
Creative#:
TOP10705353
Source:
達志影像
Authorization Type:
RM
Release Information:
須由TPG 完整授權
Model Release:
No
Property Release:
No
Right to Privacy:
No
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ANAESTHETICANALGESIAANESTHESIAANESTHETICANAESTHESIOLOGYANESTHESIOLOGYARTWORKBINDINGBIOCHEMICALBIOCHEMISTRYCELLBIOLOGYCYTOLOGYCYTOLOGICALCOMPLEXCOMPLEXEDBOUNDCHANNELCHEMICALCHEMISTRYCUTOUTCUTOUTSCUT-OUTCUT-OUTSCUTOUTCUTOUTSDRUGELECTRONDENSITYGENERALANAESTHESIAILLUSTRATIONINTERACTIONINTERACTINGINHIBITIONINHIBITINGIONCHANNELPROPOFOLLGICLGICSLIGAND-GATEDIONCHANNELMEDICALMEDICINEMOLECULARMODELMOLECULARSTRUCTUREMOLECULEMOLECULESNMDARECEPTORANTAGONISTPENTAMERICLIGAND-GATEDIONCHANNELPHARMACOLOGICALPHARMACOLOGYPLGICPLGICSPROTEINPROTEINSPROTEOMICSRECEPTORSRECEPTORSYSTEMWHITEBACKGROUNDQUATERNARYSTRUCTURESECONDARYSTRUCTURERIBBONSTRUCTURE
ANAESTHESIAANAESTHESIOLOGYANAESTHETICANALGESIAANESTHESIAANESTHESIOLOGYANESTHETICANTAGONISTARTWORKBACKGROUNDBINDINGBIOCHEMICALBIOCHEMISTRYBIOLOGYBOUNDCELLCHANNELCHANNELCHANNELCHANNELCHEMICALCHEMISTRYCOMPLEXCOMPLEXEDCUTCUTCUT-OUTCUT-OUTSCUTOUTCUTOUTSCYTOLOGICALCYTOLOGYDENSITYDRUGELECTRONGENERALILLUSTRATIONINHIBITINGINHIBITIONINTERACTINGINTERACTIONIONIONIONLGICLGICSLIGAND-GATEDLIGAND-GATEDMEDICALMEDICINEMODELMOLECULARMOLECULARMOLECULEMOLECULESNMDAOUTOUTSPENTAMERICPHARMACOLOGICALPHARMACOLOGYPLGICPLGICSPROPOFOLPROTEINPROTEINSPROTEOMICSQUATERNARYRECEPTORRECEPTORRECEPTORSRIBBONSECONDARYSTRUCTURESTRUCTURESTRUCTURESTRUCTURESYSTEMWHITE