Skin-patch allergy to nicotine. Red-weals are seen on the arm of a male patient, due to a skin allergic reaction to Nicotinelle" patches used to help subdue the urge to smoke. Nicotine is a stimulant drug found in tobacco. It increases alertness and concentration, but is addictive. The habit of smoking can be broken by use of nicotine- containing supplements that provide the blood with a lowered nicotine content, reducing an addicts craving to smoke. Here, in the second month of using "Nicotinelle" patches to help overcome his addiction (these introduce nicotine through the skin into the blood), this patient developed a sudden allergic sensitivity to the drug."