Liver cirrhosis. Gross clinical specimen of a section through a human liver suffering from cirrhosis. Cirrhosis is a disease in which bands of fibrosis (internal scarring) break up the internal structure of the liver. The surviving cells multiply to form regeneration nodules separated by scar tissue. This gives a cirrhotic liver a typical granulated aspect. Heavy alcohol consumption is the most common cause of cirrhosis in developed countries. Hepatitis, inflammation of the liver, may also lead to cirrhosis. The most common symptoms are mild jaundice, oedema, mental confusion and vomiting of blood.