Arthritic hand. Coloured X-ray of the right hand of a patient with rheumatoid arthritis. Rheumatoid arthritis is an autoimmune disorder. It occurs when the body's immune system attacks joint tissue, commonly in the hands and feet. Affected joints become painful and inflamed, limiting movement. Severe cases can lead to deformity. There is no cure for the disease, but anti-inflammatory drugs and immunosuppressants may relieve the symptoms. Physiotherapy can help to keep the joints supple, and special tools can compensate for the lack of mobility.